A Horse of a Different Color

The other day my doctor suggested a couple of Ketamine infusions to do until I can do ECT. I didn’t think much of this because I’ve done several ketamine infusions in the past and they didn’t do much for me, but I learned the clinic that I was going to in Corpus was doing the infusions wrong, or perhaps not in the ideal way. Let’s put it that way.

At the old clinic they were adding benzos (Ativan, Valium) to the ketamine, which actually lowers the efficacy of the ketamine. I didn’t know that until I got to Menninger. Also, the other clinic’s protocol was to give everyone 100mg/hour no matter what. Here, they go by weight. I was skeptical of that at first but now I see why.

When you do 100 mg per hour, rather when I do 100 mg per hour, I feel like I’m in a black hole. There’s a lot of dissociation and I just feel drugged up and then I’m tired for the rest of the day. When I tried ketamine at the clinic, it was almost a religious experience. It was the most calming, most relaxing, therapeutic experience I’ve EVER had. I felt happy – and I haven’t felt happy in a loooong time.

It was amazing. Now, this infusion lasted just 40 minutes but I’ve already noticed a shift in my behavior. I made some jokes with some of the patients and staff here. I cleaned up my room and generally my mood is a bit better. I still have depression, of course, but it did provide a respite from the constant pain I’m in.

This makes me hopeful. I’m scheduled to have another ketamine treatment Monday and then later in the week, I’m due to start ECT. I’m not expecting my life to change but I’ll take any improvement from my current state. Some days it’s just so hard to breathe and it’s so exhausting to be a wife, mother, daughter, friend, etc. It’s just painful. Everything is painful, so relief is all I want. I want to be there for everyone. I want to smile and laugh – just live in something other than this awful darkness. I know I have to work on my therapy, too, and believe me I am. Everyday here is emotionally draining and I don’t think I’ve gone a day without crying, but that’s okay. I’m just trying to get to the other side.

I hope I see ya’ll there soon.

Spravato: Treatments 1 & 2

This past week I completed my first two treatments of Spravato. What’s that, you say? It’s a nasal spray with esketamine (very much like ketamine) that helps with depression and a host of other things, such as migraines – at least for me.

My first treatment did not go well. First of all, I HATE things going up my nose. Second, it gave my a horrible taste in the back of my throat and I got a little nauseated. I also didn’t dissociate, which is one of the biggest side effects of the drug. Under the FDA’s rules I had to stay there for two hours, so I was hoping for a little dissociation, otherwise it’s just boring. So, it had no affect on me besides being a little sick to my stomach and then I was bored for two hours. Plus when I got home, I got a huge migraine and for the next two days and had to see my neurologist to get a Nubain injection for my migraines to go away. Maybe it was just a coincidence but I was annoyed and didn’t want to go for the second treatment. It had been awhile since I’d had a migraine.

But to my delight, the second treatment went well. I got the hang of putting the nasal mist up my nose, got used to the nasty taste in my throat and this time they gave me Zofran for the nausea. I still didn’t dissociate but I was tired enough to take an almost two hour nap, so the visit passed rather quickly. Can’t say the same for my husband who has to stay there the whole time and give me a ride home. FDA rules again. He can’t leave the whole two hours while I’m receiving treatment.

I don’t feel a whole lot better, and since it’s hardly affecting me, my doctor is going to bump me up to the big girl dose next week, which is about 84mg of esketamine. When I go to get the ketamine infusions at the clinic via IV, I’m receiving 100mg, plus they give me a benzo in the IV – I don’t know why they do that. So, maybe the larger dosage will help me more.

Don’t get me wrong, it wasn’t a complete failure. I do feel better after the second one but I’m still dealing with symptoms of depression. But I don’t feel as blah as I have been.

I’m supposed to go three times to the clinic next week to get the larger dose, so we’ll see how that goes.

As far as my weight loss and journey to get healthy, I haven’t even been on the scale. I’ve been eating poorly and drinking Diet Coke again. My depression just hit hard this week and the week before. I think. I can’t remember last week. I’ll get back on track and keep you guys updated. Thanks for the support.

Stay well, my friends.